If you have just watched the film, or you have just had a diagnosis and you are standing where I was standing, this is the list I wish someone had handed me in the first week.
Don't be overwhelmed by the quantity of information on this page. Start at the top and go at your own pace.
Seyfried setting out the whole argument in one sitting, at a length that lets him actually build it rather than summarise it. This is the talk linked from his own Boston College faculty page, and the best single place to begin.
The how-to: what to eat, how to track it, what to say to your oncologist. Written by a nutritionist whose own son had a brain tumour.
Proposes combining steady dietary pressure with timed drug pulses to stress tumour cells. A proposed strategy, not a tested protocol.
The argument set out in full and free to read: that cancer is fundamentally a disease of damaged mitochondria. A minority view in oncology.
The conversation that put this argument in front of a very large general audience. Long, accessible, and the one to send to someone who would never open a journal article.
Duraj is a postdoctoral fellow in Seyfried's lab and a co-author on the 2025 Greek clinical study listed further down this page. Here he sets out what that data showed and what it did not. Short.
The history of the metabolic theory told as a story rather than as science. The easiest reading on this page, and a good way to understand how the idea developed and who fought over it. Advocacy, not a neutral textbook.
Attia pushes back hard and Seyfried defends his position for two hours. The most useful thing to listen to if you want to hear the argument tested rather than presented.
The Nobel laureate's claim that cancer begins with broken cell energy machinery, not only damaged genes. Everything else here descends from this.
Mainstream cancer biology's own account of why tumours burn sugar strangely. Read it to see where orthodoxy agrees with Seyfried and where it parts company.
The full book-length case, dense and technical. The reference work if you want the primary argument rather than someone's account of it. A number of websites carry summaries of this book. None of them are written or approved by Seyfried, so read them as someone else's interpretation and not as his position.
The glutamine half of the story: cutting sugar alone is not enough, because tumours also run on an amino acid. Shown in mice, not yet in people.
Explains the glucose-ketone index, the single number people use at home to check whether their diet is doing what they hope it is.
Suggests ketones themselves, not only low blood sugar, may slow tumours. This is the research behind exogenous ketone supplements. Animal study.
The most complete public write-up of what the Press/Pulse strategy actually involves in practice, assembled by Daniel Orrego, who also co-founded the Hippocrates Research Foundation. Useful for understanding the shape of the thing. Note that it names specific drugs and gives dosing by body weight: none of that is part of standard oncology, and none of it should be attempted without a doctor supervising you.
A case report describes one person. It is the weakest form of clinical evidence and the most compelling to read. Both of those are true at once.
A 32-year-old man with glioblastoma who declined chemotherapy and radiation, alive at 80 months on strict diet alone. One patient.
From the Istanbul clinic that appears in our film: one woman with advanced breast cancer, complete response. One patient at one clinic is not proof.
Kalamian in her own words on her son Raffi, diagnosed with a brain tumour as a small boy, and how a mother with no medical training ended up building a clinical practice out of what she had to learn.
Bosworth, an internal medicine physician, put her own mother on ketogenic metabolic therapy after a cancer diagnosis and wrote the book she wished someone had handed her. Half memoir, half beginner’s manual for ketones.
Kelly was told in his twenties that his glioblastoma was inoperable. He declined chemotherapy and radiation and went the metabolic route. He tells it himself here, with no clinician mediating.
These are the ones to read if you are sceptical, or if someone you trust is.
A sober, non-partisan review of what the human evidence does and does not support. The honest counterweight to the enthusiasts, us included.
Fifty clinicians and scientists set out how this should finally be tested properly. The field's own admission that the trials have not been done.
The gold-standard evidence review showing ketogenic diets genuinely reduce seizures. Proof that diet can be real medicine, independent of any cancer claim.
Eighteen glioblastoma patients were taught ketogenic metabolic therapy alongside standard care. Six followed the diet for more than six months, and four of those six were alive at three years. Of the twelve who did not adhere, one was. That is 66.7 per cent against 8.3 per cent, in a disease whose median survival is twelve to eighteen months. Eighteen people, no randomisation, no control arm — a signal worth chasing, not a verdict.
Also eighteen patients, arrived at independently and from the other side of the world: five-day water fasts and time-restricted ketogenic eating alongside standard chemoradiation. Median survival 21.5 months against 14.7, and 27 per cent alive at three years against 7 per cent. The result holds for the fifteen who completed the programme but not across all eighteen as enrolled, which is the honest caveat.
A plain-English walk through the New Zealand trial for anyone who would rather not read the paper. Marik is an advocate, so take it as a summary rather than an appraisal.
How hospitals actually run a medical ketogenic diet safely: monitoring, side effects, supplements. The practical safety document nobody hands you.
Twenty clear minutes on why ketones and oxygen may pressure tumours, from a researcher who is careful about what is and is not proven.
A cardiologist's lecture on why periodic fasting lowers insulin and inflammation. Engaging and widely shared, but a lecture rather than evidence.
The full argument delivered to a general audience rather than a room of specialists. If you watch only one Seyfried lecture, watch this one.
Seyfried’s own channel, where he and his lab answer questions directly rather than through an interviewer.